Synthesis of 1C-Aryl/Alkyl 2C-Branched Sugar-Fused Isochroman Derivatives by Sequential Prins and Friedel–Crafts Cyclizations on a Perlin Aldehyde Derived Substrate

Autor:	Yakkala Mallikharjunarao, Parasuraman Rajasekaran, Yashwant D. Vankar
Rok vydání:	2017
Předmět:	chemistry.chemical_classification 010405 organic chemistry Aryl Organic Chemistry Alcohol Prins reaction 010402 general chemistry 01 natural sciences Aldehyde 0104 chemical sciences chemistry.chemical_compound chemistry Molecule Organic chemistry Selectivity Friedel–Crafts reaction Alkyl
Zdroj:	Synlett. 28:1346-1352
ISSN:	1437-2096 0936-5214
Popis:	The synthesis of C-aryl/alkyl 2C-branched sugar-fused isochromans by using a carbohydrate-derived starting material is described. Our approach makes use of sequential Prins and Friedel–Crafts cyclizations in which a Perlin aldehyde derived homoallylic alcohol is converted into the target molecule. This strategy works well with many aldehydes and gives good yields with excellent selectivity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9ec25be10477535771a1b1413e9ee8f5 https://doi.org/10.1055/s-0036-1588156 Zobrazit plný text záznamu