High dose versus low dose Aspirin after Percutaneous Coronary Intervention in Coronary Artery Disease

Autor:	Satish Singh, Yuba Raj Limbu, Rikesh Tamrakar, Sanjay Singh Kc, Rajib Rajbhandari
Rok vydání:	2019
Předmět:	Coronary artery disease medicine.medical_specialty business.industry Internal medicine medicine.medical_treatment medicine Cardiology Percutaneous coronary intervention medicine.disease business Low dose aspirin
Zdroj:	Nepalese Heart Journal. 16:59-62
ISSN:	2382-5464 2091-2978
DOI:	10.3126/njh.v16i2.26319
Popis:	Background and Aims: Patients with Coronary artery disease who undergo percutaneous coronary intervention (PCI) are prescribed with maintenance aspirin dose that vary between 75 mg to 300 mg daily. The objective of this study is to evaluate the effects of high dose versus low dose aspirin doses prescribed on hospital discharge in PCI. Methods: All the patients who had undergone PCI at our hospital from 2017 February to October 2017 were enrolled in the study. They were divided into two groups receiving low dose (200mg) aspirin. Patients were interviewed on phone after completion of one year for the possible complications and new ischemic events during the follow up period. Results: Among 150 patients selected 101 fulfilled the criteria and sixty patients (59.4%) were discharged on low-dose aspirin 75-150mg and 41 patients (40.6%) were discharged on high-dose aspirin of 300mg. The mean age in low aspirin group was 59.8±13.19 years and 49.4±10.7 years in high aspirin group. Although high aspirin dose patients did not complain of epigastric pain more often, upper GI bleeding was significantly higher in high aspirin group 7.5% vs 11.1% (p
Databáze:	OpenAIRE
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