ChemInform Abstract: Rapid Two-Step Synthesis of Drug-Like Polycyclic Substances by Sequential Multi-Catalysis Cascade Reactions

Autor:	Chintalapudi Venkaiah, Rumpa Mondal, Dhevalapally B. Ramachary
Rok vydání:	2010
Předmět:	Cascade Chemistry Organocatalysis Two step Salt metathesis reaction General Medicine Combinatorial chemistry Catalysis
Zdroj:	ChemInform. 41
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.201021098
Popis:	An efficient amino acid-/self-/base-/ruthenium-/thermal-catalyzed two-step process for the synthesis of functionalized drug-like carbocycles was achieved through combinations of cascade TCRA/C-allylation/enyne-RCM/Diels–Alder reactions as key steps starting from simple acyclic substrates. In this communication, we report the two-step synthesis of drug-like carbocycles through a combination of organocatalysis with ruthenium-catalysis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9d21645cbd130a36ce70b93cfd09e879 https://doi.org/10.1002/chin.201021098 Zobrazit plný text záznamu Plný text