New norclerodane diterpenoids from Dioscorea bulbifera

Autor:	Hui-wen Liu, Juan Zheng, Yun-Peng Sun, Zhong-Yu Zhou, Wen-Fang Jin, Jin-Song Liu, Yang Yu, Guo-Kai Wang
Rok vydání:	2018
Předmět:	Traditional medicine biology 010405 organic chemistry Chemistry Dioscorea bulbifera Plant Science biology.organism_classification 01 natural sciences Biochemistry 0104 chemical sciences 010404 medicinal & biomolecular chemistry Cancer cell lines Agronomy and Crop Science Biotechnology
Zdroj:	Phytochemistry Letters. 27:59-62
ISSN:	1874-3900
DOI:	10.1016/j.phytol.2018.06.025
Popis:	Three new norclerodane diterpenoids, diosbulbin E acetate (1), diosbulbin R (2), and diosbulbin S (3), and seven known compounds (4-10) were isolated from an ethanol extract of Dioscorea bulbifera tubers. The structure of compounds 1–10 was determined through extensive NMR and mass spectroscopic analyses. The new compounds were investigated to determine their cytotoxic activity against the SMMC-7721 cancer cell line.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9cb903bd0e7eb99dcc042c496144598a https://doi.org/10.1016/j.phytol.2018.06.025 Zobrazit plný text záznamu Full Text from ScienceDirect