Mechanism of pH influence on aptamer binding with Cd2+ revealed by molecular dynamics simulation

Autor: Hongen Yuan, Xiuxiu Wu, Xingfa Ren, Bin Xue, Wenjie Qiu, Dinghui Nong, Tao Yang, Fei Xu
Rok vydání: 2023
Předmět:
Zdroj: New Journal of Chemistry. 47:9239-9249
ISSN: 1369-9261
1144-0546
DOI: 10.1039/d2nj06122h
Popis: pH decrease changes the interbase hydrogen bonds and negative charge of the aptamer, destroying its affinity for Cd2+.
Databáze: OpenAIRE