Some Aspects of the Biological Role of Adenosine 3',5'-monophosphate (Cyclic AMP)

Autor:	G. Alan Robison, Earl W. Sutherland, R.W. Butcher
Rok vydání:	1968
Předmět:	Adrenal disorder Adenylate kinase Phosphodiesterase Biology Adenosine Glucagon Adenosine 3 5 monophosphate Biochemistry Physiology (medical) Second messenger system medicine Cardiology and Cardiovascular Medicine medicine.drug Hormone
Zdroj:	Circulation. 37:279-306
ISSN:	1524-4539 0009-7322
Popis:	Cyclic AMP (adenosine 3',5'-monophosphate or cyclic adenylate) has now been established as a second messenger mediating many of the effects of a variety of hormones. Several of the metabolic effects mediated by cyclic AMP are discussed, and it is suggested that certain other ("functional" or "mechanical") hormonal effects may be similarly mediated. In particular, the evidence presented supports the hypothesis that the positive inotropic response to the catecholamines is mediated by cyclic AMP. Although knowledge of the biological role of cyclic AMP has not been widely applied clinically, sufficient knowledge has now accumulated to make research in this area desirable.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9a908a2dda64d28a92b072f22f28ffd0 https://doi.org/10.1161/01.cir.37.2.279 Zobrazit plný text záznamu