A highly efficient In(OTf)3-catalyzed [3 + 3] annulation of spirocyclopropyl oxindoles with 1,4-di-thiane-2,5-diol

Autor:	Zhong-Yan Cao, Jian Zhou, Yong-Jia Hao, Ying Zhou, Yi Gong
Rok vydání:	2020
Předmět:	Annulation Thiopyran Diol Thiane 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Combinatorial chemistry 0104 chemical sciences Catalysis chemistry.chemical_compound chemistry 0210 nano-technology
Zdroj:	Chinese Chemical Letters. 31:681-684
ISSN:	1001-8417
DOI:	10.1016/j.cclet.2019.08.018
Popis:	Spirooxindoles play an important role in drug discovery and development. The development of efficient methods for the synthesis of spirooxindoles from easily available starting materials is of current interest. Herein, we report in detail the In(OTf)3-catalyzed [3 + 3] annulation of spirocyclopropyl oxindoles and 1,4-di-thiane-2,5-diol, which allows the facile preparation of spiro[indoline-3,4′-thiopyran]-2-ones bearing (tetrahydro)thiopyran skeleton.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::9868e9cd73b67050360183a73ca5f863 https://doi.org/10.1016/j.cclet.2019.08.018 Zobrazit plný text záznamu Full Text from ScienceDirect