Increase in calcium content of erythrocyte and its significance to the function of enzyme calcium activated neutral protease (CANP) activity in β- thalassemia homozygotes and heterozygotes

Autor:	Ch. V. Ramana Devi, M. P. J. S. Anandaraj
Rok vydání:	1994
Předmět:	chemistry.chemical_classification medicine.diagnostic_test biology Proteolysis Thalassemia Clinical Biochemistry chemistry.chemical_element Heterozygote advantage Calcium medicine.disease In vitro Membrane glycoproteins Cytosol Enzyme chemistry Biochemistry medicine biology.protein sense organs
Zdroj:	Indian Journal of Clinical Biochemistry. 9:21-23
ISSN:	0974-0422 0970-1915
Popis:	The enhanced presence of calcium in the erythrocytes of thalassemia homozygotes along with an increase in cytosolic and membrane bound CANP, and a decrease in membrane glycoprotein and total membrane sulfhydryl groups are statistically significant changes.In vitro loading of erythrocytes with calcium in the presence of lonophore A23187 caused similar changes pointing to the significance of calcium mediated proteolysis, especially by CANP in preparing erythrocytes for the phagocytic event.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::97e03a94a92166b2557499717f4fde2e https://doi.org/10.1007/bf02867848 Zobrazit plný text záznamu Full text from SpringerLink