Antiseptics and Antisepsis

Autor: Gerald E. McDonnell
Rok vydání: 2017
Předmět:
Zdroj: Antisepsis, Disinfection, and Sterilization ISBN: 9781683670858
DOI: 10.1128/9781555819682.ch4
Popis: Antiseptics can be defined as biocidal products that destroy or inhibit the growth of microorganisms in or on living tissue, e.g., on the skin. In theory, any biocide or biocidal process could be used on the skin or mucous membranes, although only a small number are widely used. Living tissues are more sensitive to damage than hard surfaces; therefore, the requirements for safe use restrict the use of antiseptics to those that have limited or no toxicity. Antiseptics can include a variety of formulations and preparations such as antimicrobial hand-washes, hand-rubs (“sanitizers”), surgical scrubs, preoperative preparations, ointments, creams, tinctures, mouthwashes, and toothpastes. Overall, antiseptics should demonstrate the following characteristics: A wide spectrum of biocidal activity, in particular, against bacteria, fungi, and viruses Rapid biocidal activity Little or no damage, irritation, or toxicity to the tissue Little or no absorption into the body If possible and applicable, some persistent biocidal (or biostatic) activity (Many biocides used in antiseptics can remain on the skin following washing or application, allowing for continuing biocidal or growth-inhibitory action over time.)
Databáze: OpenAIRE