A Streptococcus pneumoniae (pneumococcus) -infekciók ezer arca

Autor: Andrea Gombos, Katalin Szidonia Lenart, Judit Szanka, Gyula Prinz, Ilona Bobek, Balint Gergely Szabo, Balázs Dezsényi, Béla Kádár
Rok vydání: 2015
Předmět:
Zdroj: Orvosi Hetilap. 156:1769-1777
ISSN: 1788-6120
0030-6002
Popis: Incidence and mortality rates of infections caused by Streptococcus pneumoniae (pneumococcus) are high worldwide and in Hungary among paediatric as well as adult populations. Pneumococci account for 35–40% of community acquired adult pneumonias requiring hospitalization, while 25–30% of Streptococcus pneumoniae pneumonias are accompanied by bacteraemia. 5–7% of all infections are fatal but this rate is exponentially higher in high risk patients and elderly people. Mortality could reach 20% among patients with severe invasive pneumococcal infections. Complications may develop despite administration of adequate antibiotics. The authors summarize the epidemiology of pneumococcal infections, pathogenesis of non-invasive and invasive disease and present basic clinical aspects through demonstration of four cases. Early risk stratification, sampling of hemocultures, administration of antibiotics and wider application of active immunization could reduce the mortality of invasive disease. Anti-pneumococcal vaccination is advisable for adults of ≥50 years and high risk patients of ≥18 years who are susceptible to pneumococcal disease. Orv. Hetil., 2015, 156(44), 1769–1777.
Databáze: OpenAIRE