A multicentred phase III comparatiye study between single-implant containing 3-ketodesogestrel (Implanon®) and implants containing levonorgestrel (Norplant®) I. Effïcacy, acceptability and safety (three-year results)

Autor:	T.B. Paul Geurts, Rizani Amran, Fitriani Iskandar, H. J. T. Coelingh Bennink, Lila Dewata, Tjeerd Korver, Agus Sopacua, R.P. Barus, N.P. Noerpramono, Biran Affandi, W. Ngartjono, H.M. Hoesni
Rok vydání:	1999
Předmět:	medicine.medical_specialty business.industry Single implant medicine Levonorgestrel General Medicine Implant Continuation rate business 3-Ketodesogestrel Subdermal implant Surgery medicine.drug
Zdroj:	Medical Journal of Indonesia. :49
ISSN:	2252-8083 0853-1773
DOI:	10.13181/mji.v8i1.677
Popis:	With the objective to evaluate the efftcacy, acceptability and safety of subdermal-single-rod ethylene vinyl acetate (EVA) implant contraceptive containing 68 mg j-ketodesogestrel (Implanon@), a multicentred comparative srudy has been conducted between Implanon@ and NorplanP (subdermal implant contraceptive consisting of six siktstic capsules, each capsule containing 36 mg levonorgestrel). A total of 898 women were recruited into an eight centre, randomized clinical trinl. One subject was excludedfrom the study because she had been already pregnant when the implant inserted. Follow up scheduled fqr 3 years. The mean insertion time was 0.8 minute for Implanon@ and 4.4 minutes for NorplanP. The mean removal time was 4.9 minutes for Implanon@ and 30.2 minutes for Norplan9. These dffirences are statiscally significant (p
Databáze:	OpenAIRE
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