A REVIEW ON THE APPLICATION OF SOLID LIPID NANOPARTICLES IN TRANSDERMAL PATCH DRUG DELIVERY

Autor: Aastha Arora, Harsh Gupta, Pankaj Sharma, Kamini, Rabnoor Alam
Rok vydání: 2021
Předmět:
Zdroj: International Research Journal of Pharmacy. 12:6-20
ISSN: 2230-8407
DOI: 10.7897/2230-8407.1209160
Popis: The transdermal patches are used to deliver medication through the skin to treat the entire ailment. These depend on a unique size property of skins to encoded drugs solid lipid nanoparticles (SLNs) current a chance to create upon novel therapeutic properties used for drugs transmission SLN targeting holds great potential for target achieving, a penalty area, Many aspects of the loaded of SLN sin transdermal patches for increasing mechanism of penetration, formulation, characterization parameters, future advantages, limitations of SLNs, had better biocompatibility, low harmfulness, SLNs is physically stable, and better delivery for Lipophilic drugs are discussed here. SLNs are a hybrid of liposomes and polymer-based carriers that could be used to encapsulate both lipid and water-soluble medicines. SLN is a low-cost product that can be scaled up. They also have a long-life span and could be customized by using different lipids. Because of their multiple significant qualities, SLNs also started to emerge when effective drug delivery carriers, as well as the prospect with liposome delivery of drugs, depends heavily on them. Many patents relating to SLNs have already been submitted, there are more invented SLN-based delivery systems on the way soon.
Databáze: OpenAIRE