Thrombotic thrombocytopenic purpura as the initial presentation of COVID‐19
| Autor: | Marie-Claude Beaulieu, Michèle Mahone, Benjamin Rioux-Massé, Danny Sebastien Mettelus |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Microangiopathy Thrombotic thrombocytopenic purpura Complete blood count Inflammation Hematology Microangiopathic hemolytic anemia 030204 cardiovascular system & hematology Immune dysregulation medicine.disease medicine.disease_cause Gastroenterology 03 medical and health sciences 0302 clinical medicine hemic and lymphatic diseases Internal medicine medicine medicine.symptom Presentation (obstetrics) business Computed tomography of the head |
| Zdroj: | Journal of Thrombosis and Haemostasis. 19:1132-1134 |
| ISSN: | 1538-7836 |
| Popis: | A 70-year-old man who tested positive for SARS-CoV-2 presented to the hospital with confusion and a seizure. A computed tomography of the head was normal. The initial complete blood count showed severe thrombopenia and microangiopathic hemolytic anemia. Low ADAMTS13 activity confirmed the diagnosis of thrombotic thrombocytopenic purpura (TTP). Treatment with corticosteroids and plasma exchange was successful and the patient recovered completely. As no other causes were found, COVID-induced TTP was diagnosed. A combination of inflammation and immune dysregulation could explain this presentation. |
| Databáze: | OpenAIRE |
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