Aberrant lymphatic drainage and risk for melanoma recurrence after negative sentinel node biopsy in middle-aged and older men
| Autor: | Anthony Kaveh, Aaron J. Berger, Susan M. Swetter, Frank W. Chen, John B. Sunwoo, Mike Yao, Melynda A. Barnes, Andrew Quon, Denise L. Johnson, Sean Parsa, Nicole M. Seminara |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry Melanoma Sentinel lymph node Sentinel node medicine.disease Surgery 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Lymphatic system Otorhinolaryngology 030220 oncology & carcinogenesis Biopsy medicine Sampling (medicine) Clinical significance Drainage business |
| Zdroj: | Head & Neck. 38:E754-E760 |
| ISSN: | 1043-3074 |
| DOI: | 10.1002/hed.24094 |
| Popis: | Background Aberrant lymphatic drainage is believed to contribute to the high recurrence rate of head and neck melanomas. The purpose of this study was to identify the clinical significance of unexpected lymphatic drainage patterns. Methods A single institution retrospective analysis was performed of middle-aged and older men (mean age, 66.2 years; range, 41–87 years) who underwent successful lymphoscintigraphy with sentinel lymph node biopsy (SLNB) from 1997 through 2012. Node status, distribution, and recurrence were assessed comparing patients with expected and unexpected drainage patterns. Results Sixty-six patients were identified with 55.8 months median follow-up (range, 5.6–206.1 months). Unexpected sentinel lymph node drainage was associated with multiple basin drainage (p |
| Databáze: | OpenAIRE |
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