| Autor: |
Youssef Fihri, Driss Britel, Nada Alloul, Hicham Faliouni, Zakaria Lahlafi, Soumia Faid, Masrar Azelarab, Aatef Benyass, Zouhair Lakhal |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
SAS Journal of Medicine. 9:362-366 |
| ISSN: |
2454-5112 |
| DOI: |
10.36347/sasjm.2023.v09i04.029 |
| Popis: |
Von willbrand syndrome remains a rare pathology. Its etiologies and clinical manifestations are varied. This syndrome can be inherited or acquired. The acquired form is associated with various pathologies (Gastric, mechanical support system…) including cardiovascular diseases such as aortic stenosis, HCM, and Mitral regurgitation. Nevertheless, the association of acquired Willebrand syndrome with coronary pathology remains a rare association. In this literature review, we have made a review of the various articles addressing this subject. The management of ACS in patients with AvWS follows that of normal patients in terms of interventional procedure, however therapeutic drug management remains delicate given the hemorrhagic risk that these drugs present. The use of DAPT and heparin is possible while thrombolysis remains at very high risk for the patient. The use of desmopressin can be done with caution and also factor VIII and vWF concentrates have their place to reduce the risk of bleeding. Overall, the collaboration of the cardiologist and hematologist remains essential for better management of these patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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