Synthesis of Substituted Indole-3-carboxylates by Iron(II)-Catalyzed Domino Isomerization of 3-Alkyl/aryl-4-aryl-5-methoxyisoxazoles

Autor:	Alexander F. Khlebnikov, Vladimir A. Bodunov, Ekaterina E. Galenko, Alexey V. Galenko, Mikhail S. Novikov
Rok vydání:	2018
Předmět:	Indole test chemistry.chemical_classification Tandem 010405 organic chemistry Aryl Organic Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry Catalysis Domino 0104 chemical sciences chemistry.chemical_compound chemistry Atom economy Isomerization Alkyl
Zdroj:	Synthesis. 50:2784-2798
ISSN:	1437-210X 0039-7881
DOI:	10.1055/s-0036-1591576
Popis:	The iron(II)-catalyzed domino isomerization of 3-alkyl/aryl-4-arylisoxazoles provides a selective access to a wide range of structurally diverse highly substituted indole-3-carboxylates. The operational simplicity, high atom efficiency, and the use of stable starting materials and an inexpensive and low-toxicity catalyst are some of the attractive features of this tandem double ring-opening–ring-closure strategy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::91cb280917ff4a2c9d2d7c72341acdb0 https://doi.org/10.1055/s-0036-1591576 Zobrazit plný text záznamu