Antioxidant and antibacterial activities of Ischaemum indicum leaves extracted using different solvents
| Autor: | Sri Fatmawati, Hamdan Dwi Rizqi, Adi Setyo Purnomo, Fithrotul Auwaliyah |
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| Rok vydání: | 2019 |
| Předmět: |
Chromatography
Antioxidant ABTS biology DPPH General Mathematics medicine.medical_treatment Ethyl acetate General Physics and Astronomy General Chemistry Bacillus subtilis biology.organism_classification General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound chemistry medicine Methanol General Agricultural and Biological Sciences Antibacterial activity Dichloromethane |
| Zdroj: | Malaysian Journal of Fundamental and Applied Sciences. 15:436-440 |
| ISSN: | 2289-599X 2289-5981 |
| DOI: | 10.11113/mjfas.v15n3.1037 |
| Popis: | The aim of this study was to evaluate antioxidant and antibacterial activities of Ischaemum indicum leaves extracts based on different polarity solvents: water, methanol, ethyl acetate, dichloromethane, and n- hexane. The antioxidant activity was evaluated using ABTS and DPPH methods, while the antibacterial activity was determined by broth dilution method against Pseudomonas aeruginosa and Bacillus subtilis . The results showed that water and methanol extracts of I. indicum gave the highest antioxidant activity in ABTS assay with an IC 50 73.80 and 46.32 µg/mL, respectively. On the other hand, The IC 50 on DPPH assay for water extracts was 117.51 µg/mL, this value was higher than that of methanol extract with no inhibition. Methanol and water extracts showed the antibacterial activity against B. subtilis with inhibition of 48.62 and 45.11%, whereas inhibition of P. aeruginosa were 31.95 and 30.31%, respectively. This study denoted that I. indicum is a new potential candidate as antioxidant source. |
| Databáze: | OpenAIRE |
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