| Popis: |
Background: Inflammation can be involved in developing diabetes and its related complications. In the present study, the association of dietary inflammatory index (DII) and cardiometabolic risk factors in diabetic and non-diabetic individuals have been compared. Methods: In this cross-sectional study, 9039 participants from baseline data of the Ravansar Non-Communicable Disease (RaNCD) cohort; including patients with type 2 diabetes mellitus (T2DM) (n=785) and non-T2DM cases (n=8254) were included. Logistic regression analysis was conducted to determine the association between DII and main cardiometabolic risk factors in diabetic and non-diabetic populations. All analyses were performed using Stata version 14.2 software. Results: Mean age of the study population was 47.4±8.2 years and around 46% of them were men. The total mean DII score was -2.49±1.59. After adjustment for confounding factors, we found that DII can increase the risk of T2DM by 61% (95% CI:1.27 to 2.05). A comparison of the two groups also revealed that only the association of DII, obesity/overweight and dyslipidemia were significant in both diabetic and non-diabetic ones. However, no significant association was found between DII, MetS, and hypertension in either group. The association between DII and cardiovascular diseases (CVDs) was significant in only diabetic patients 1.65 (95%CI: 1.02 to 2.65) and T2DM showed an interaction with the association between DII and CVDs. Conclusions: Inflammatory potential of diet can increase the risk of T2DM. Although it can increase the risk of some cardiometabolic risk factors in both diabetic and non-diabetic cases, its effects in patients with T2DM were greater than in non-diabetic ones. |
