Synthesis of 2-aryl-3H-naphtho[1,2-d]imidazoles containing an adamantane fragment

Autor:	N. A. Gavrilova, T. A. Frolenko, E. S. Semichenko, George A. Suboch, Alexander A. Kondrasenko
Rok vydání:	2013
Předmět:	chemistry.chemical_classification Chloroform Stereochemistry Adamantane Aryl Organic Chemistry Intramolecular cyclization Medicinal chemistry Toluene chemistry.chemical_compound chemistry Imidazole Triethylamine Alkyl
Zdroj:	Russian Journal of Organic Chemistry. 49:1748-1752
ISSN:	1608-3393 1070-4280
DOI:	10.1134/s1070428013120075
Popis:	N2-[1-(1-Adamantyl)alkyl]naphthalene-1,2-diamines reacted with benzoyl chlorides in chloroform in the presence of triethylamine to give N-{2-[1-(1-adamantyl)alkylamino]naphthalen-1-yl}benzamides which underwent intramolecular cyclization to 2-aryl-3H-naphtho[1,2-d]imidazoles on heating in toluene in the presence of p-toluenesulfonic acid. 3-[(1-Adamantyl)methyl]-2-(3-nitrophenyl)-3H-naphtho[1,2-d]imidazole was synthesized from N2-[(1-adamantyl)methyl]naphthalene-1,2-diamine and 3-nitrobenzaldehyde.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::90ab423db66a6d2677e34a6ad0195ea4 https://doi.org/10.1134/s1070428013120075 Zobrazit plný text záznamu Plný text ve formátu PDF