Hypertension intracrânienne idiopathique et mutation du facteur V de Leiden

Autor:	N. Daoussi, Samia Younes, M.H. Sfar, Saida Jerbi, Y. Cherif, M. Frih Ayed, Mouna Aissi, Amel Boughammoura
Rok vydání:	2014
Předmět:	Pathogenesis medicine.medical_specialty business.industry Internal medicine Mutation (genetic algorithm) Factor V Leiden medicine Activated protein C resistance Cardiology and Cardiovascular Medicine medicine.disease business Thrombosis Gastroenterology
Zdroj:	Journal des Maladies Vasculaires. 39:270-273
ISSN:	0398-0499
DOI:	10.1016/j.jmv.2014.04.012
Popis:	Activated proteinC resistance is a frequent prothrombotic abnormality. In most cases it is due to factorV Leiden mutation by nucleotide G1691A substitution. This recently described thrombophilic defect of activated proteinC resistance has been postulated to be implicated in the pathogenesis of idiopathic intracranial hypertension (IIH). We report a case of factorV Leiden mutation in association with IIH and their likely link and implication in the management of IIH.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::8e738e83744b3090bfae67978d8dee3d https://doi.org/10.1016/j.jmv.2014.04.012 Zobrazit plný text záznamu Full Text from ScienceDirect