| Popis: |
Obesity is an abnormal condition in which excessive fat is accumulated in adipose tissue. It has emerged as one of the biggest public health concerns today as it is a major risk factor for developing type 2 diabetes, cardiovascular disease, hypertension, and certain types of cancer. Carotenoids play a key role in maintaining health and preventing diseases because of their remarkable structural and physical properties involving antioxidant, antiinflammatory, and anticancer activities, which render them a remarkable position in the amelioration of various metabolic syndromes. In vitro and in vivo as well as human-interventional studies dealing with carotenoids shed light on the targets of major regulatory mechanisms of adipogenesis and pathophysiology concerning obesity and related metabolic disorders. This chapter primarily focuses on the antiobese molecular mechanisms of carotenoids particularly targeting adipocyte differentiation, thermogenesis, inflammation, and lipogenesis in view toward the management of obesity. |
