Glomerular and tubular function following orthotopic liver transplantation in children treated with tacrolimus
| Autor: | K. Anastaze Stelle, Valérie Anne Mclin, Eric Girardin, Dominique Charles Belli, Barbara E. Wildhaber, A. Giroud, Paloma Maria Parvex |
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| Rok vydání: | 2011 |
| Předmět: |
Transplantation
medicine.medical_specialty Orthotopic liver transplantation business.industry Urology Renal function Glomerular function Tacrolimus Medium term Nephrotoxicity Surgery Normal renal function surgical procedures operative Pediatrics Perinatology and Child Health medicine Postoperative phase business |
| Zdroj: | Pediatric Transplantation. 16:250-256 |
| ISSN: | 1397-3142 |
| DOI: | 10.1111/j.1399-3046.2011.01625.x |
| Popis: | The aim of this study was to analyze the impact of TAC on medium term (three-yr follow-up) renal function in pediatric liver transplant (OLT) recipients. Glomerular and tubular indices were retrospectively analyzed in 24 consecutive OLT pediatric recipients on TAC. CrCl increased significantly each month post-OLT (p = 0.003), with a trend toward significance between pre-OLT and 36 months (p = 0.17). There was no correlation between CrCl and TAC troughs (p = 0.783). Sixteen percent of patients had CrCl |
| Databáze: | OpenAIRE |
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