A case of coexistence between JAK2V617F and BCR /ABL

Autor: Marilina Amabile, Maurizio Roberto Longinotti, Simonetta Pardini, Claudio Fozza, Gianantonio Rosti, Emanuela Ottaviani, Elena Rimini, Salvatore Contini
Rok vydání: 2008
Předmět:
Zdroj: European Journal of Haematology. 81:75-76
ISSN: 1600-0609
0902-4441
Popis: Very recently the JAK2V617F mutation has been described in BCR⁄ABL+ patients for the first time. Even though characterized by very different clinical patterns, these cases raise some questions about the biological meaning of the coexistence between these disease-specific molecular markers. The present report confirms that the unexpected coexistence between these two disease-specific molecular markers - the JAK2V617F mutation and the BCR⁄ABL translocation - is possible.
Databáze: OpenAIRE