Binocular 3-D otolith-ocular reflexes: responses of chinchillas to natural and prosthetic stimulation after ototoxic injury and vestibular implantation

Autor: Margaret R. Chow, Celia Fernandez Brillet, Kristin N. Hageman, Dale C. Roberts, Andrianna I. Ayiotis, Razi M. Haque, Charles C. Della Santina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Neurophysiology. 129:1157-1176
ISSN: 1522-1598
0022-3077
DOI: 10.1152/jn.00445.2022
Popis: Previous studies to expand the scope of prosthetic stimulation of the otolith end organs showed that selective stimulation of the utricle and saccule is possible. This article further defines those possibilities by characterizing a diseased animal model and subsequently studying its responses to electrical stimulation alone and in combination with mechanical motion. We show that we can partially restore responses to tilt and translation in animals with unilateral gentamicin ototoxic injury and contralateral surgical disruption.
Databáze: OpenAIRE