Long-term luminescence of sensibilizers in tissues at the conditions of oxygen deficiency due to photodynamic effect
| Autor: | S. N. Letuta, S. N. Pashkevich, E. K. Alidzhanov, Yu. D. Lantukh, A. T. Ishemgulov |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
inorganic chemicals
0301 basic medicine Xanthene Quenching (fluorescence) Chemistry Singlet oxygen chemistry.chemical_element Photochemistry 01 natural sciences Oxygen Fluorescence Atomic and Molecular Physics and Optics Electronic Optical and Magnetic Materials 010309 optics 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology 0103 physical sciences Halogen Photosensitizer Luminescence |
| Zdroj: | Optics and Spectroscopy. 123:828-834 |
| ISSN: | 1562-6911 0030-400X |
| DOI: | 10.1134/s0030400x1711008x |
| Popis: | Long-term luminescence of organic dyes (xanthene dyes, halogen substituted fluoroscein) was used for an in vitro study of the photodynamic effect of exogenic probes in malignant tumors and healthy tissues of mice. It is shown that the photodynamic activity of oxygen and the dynamics of its concentration in tissues can be estimated from the delayed fluorescence of exogenic probes caused by singlet–triplet annihilation of singlet oxygen and excited triplet states of the molecules of photosensitizer dyes. It is found that quenching of long-term luminescence of photosensitizers significantly differs in tumors and normal tissues. |
| Databáze: | OpenAIRE |
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