Phytochemical characterization, Antioxidant and Analgesic potentials of Aerial Parts of Eruca vesicaria

Autor: Sihem Halmi, null Madi Aicha, null Cherfia Radia, null Zeghad Nadia, null Beroual Katiba
Rok vydání: 2022
Zdroj: South Asian Journal of Experimental Biology. 12:576-584
ISSN: 2230-9799
DOI: 10.38150/sajeb.12(5).p576-584
Popis: Our work is based on the phytochemical study, the antioxidant and the analgesic activities of a hydroalcoholic extract of Eruca vesicaria aerial part very used in traditional medicine. The phytochemical screening highlighted the presence of tannins, flavonoids, sterols, flavonoid glucosides, saponins, phenols and alkaloids. The determination of total phenols of hydromethanolic extract by the Folin-ciocalteu method revealed a content equal to 4.63 ± 0.017 mg GAE / g extract. The amount of flavonoids by AlCl3 method achieved a content equal to 2.14 ± 0.025 mg QE/ g extract. The antiradical activities were evaluated by two chemical tests ; DPPH and FRAP. The obtained results showed a high reducing activity. Besides, the acute toxicity and the analgesic activity of the plant extract was evaluated on rats, using a pain model induced by chemical stimuli, hot plate and tail immersion methods. The extract was used at various doses 100, 200 and 300 mg/kg, whereas acetylsalicylic acid was used as the standard drug (200 mg/kg). In the acetic acid-induced model, the plant extracts and the standard drug significantly (p
Databáze: OpenAIRE