Risk of Seizures After Measles-Mumps-Rubella Immunization

Autor:	Marie R. Griffin, Wayne A. Ray, Edward A. Mortimer, Gerald M. Fenichel, William Schaffner
Rok vydání:	1991
Předmět:	Pediatrics Perinatology and Child Health bacteria biochemical phenomena metabolism and nutrition
Zdroj:	Pediatrics. 88:881-885
ISSN:	1098-4275 0031-4005
Popis:	To evaluate the risks of seizures and other neurologic events following measles-mumps-rubella (MMR) or measles-rubella (MR) immunization, a retrospective cohort study was conducted among 18 364 Tennessee children enrolled in Medicaid who received MMR or MR immunizations in their first 3 years of life. One hundred children had seizures at some time between immunization and 36 months; there were no encephalopathies during this period. Four children had febrile seizures in the 7 through 14 days following MMR or MR immunization compared with 72 in the interval 30 or more days following MMR or MR immunization yielding a relative risk (95% confidence interval) of 2.1 (0.7 to 6.4). Although not statistically significant, this increase in febrile seizures in the 7- through 14-day interval following MMR immunization is coincident with the occurrence of fever following MMR immunization and is consistent with reports of other investigators.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::89264bdfdc361489807946fb51dbf462 https://doi.org/10.1542/peds.88.5.881 Zobrazit plný text záznamu