Immunohistochemistry on Histological Sections from Small (50 mg) Samples of Pulverized Breast Cancer

Autor:	Gary M. Clark, William L. McGuire, D. Craig Allred, Atul K. Tandon
Rok vydání:	1993
Předmět:	Prognostic factor Pathology medicine.medical_specialty Histology Chemistry Estrogen receptor medicine.disease Tumor Bank Medical Laboratory Technology Breast cancer Microscopic Anatomy medicine Immunohistochemistry Anatomy
Zdroj:	Journal of Histotechnology. 16:117-120
ISSN:	2046-0236 0147-8885
Popis:	A method is described for making histological sections of tumor pellets prepared from very small particulate samples of breast cancer originally pulverized for biochemical analysis of estrogen and progesterone receptors. Pulverizing the frozen tumor fractures it into fine particles with remarkably intact microscopic anatomy. This method embeds and concentrates the particles in matrices suitable for preparation of either frozen or permanent histological sections. We have used these tumor pellets and standard immunohistochemical procedures to study multiple biologically and prognostically important markers on single 50 mg samples of breast cancer from a large frozen tumor bank with long-term clinical follow-up. (The J Histotechnol 16:117, 1993)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::88298f829ebddf7cfd0665abe7e6278d https://doi.org/10.1179/his.1993.16.2.117 Zobrazit plný text záznamu