RUSIP SEHUBUNGAN PROFIL LIPID DALAM KEADAAN HIPERKOLESTEROLEMIA
Autor: | Indranila Ks, Satrianugraha |
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Rok vydání: | 2018 |
Předmět: | |
Zdroj: | INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY. 20:97-102 |
ISSN: | 2477-4685 0854-4263 |
DOI: | 10.24293/ijcpml.v20i2.1074 |
Popis: | Rusip is a fermented fish product made from anchovies. Several lactic acid bacteria have been identified in rusip fermentation. Lacticacid bacteria are known to be able to reduce serum cholesterol. The aim of the research was to know the lipid profile changes due toadministration of rusip in hypercholesterolemia rats. The research was done by using Pre and Post Randomized Controlled Group Design.The research subjects consisted of twenty-eight Sprague Dawley strain white male rats aged 20 weeks with normal body weight, who weregiven a high-fat high-cholesterol diet, then divided into four (4) groups: control group, without Rusip administration; P1, P2 and P3 whoreceived 2.55; 5.10 and 7.65 mg Rusip/g body weight. After 14 days treatment, blood samples were taken to determine the lipid profileusing enzymatic methods. ANOVA or alternative test, was used to test the difference between the groups at the 95% confidence level. Basedon the research, the administration of Rusip in the treatment group caused significant changes in the lipid profiles of hypercholesterolemiarats (p |
Databáze: | OpenAIRE |
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