Demonstrating Encapsulation and Release: A New Take on Alginate Complexation and the Nylon Rope Trick

Autor:	Inge R. Schlager, Stephen W. Wright, Andrienne C. Friedli
Rok vydání:	2005
Předmět:	Aqueous solution Coacervate Chemistry General Chemistry Chloride Education Chitosan chemistry.chemical_compound Membrane Diamine Polymer chemistry medicine Chelation Nylon rope trick medicine.drug
Zdroj:	Journal of Chemical Education. 82:1017
ISSN:	1938-1328 0021-9584
Popis:	Three variations on a classroom demonstration of the encapsulation of droplets and evidence for release of the interior solution are described. The first two demonstrations mimic biocompatible applications of encapsulation. Reversible formation of capsules from aqueous solutions of sodium alginate, a negatively charged polysaccharide derived from kelp, is shown by cross-linking with Ca2+ ionsand decomplexation with monovalent ions or a chelating agent. Rapid release ofcitric acid from a complex coacervate of alginate with chitosan, a positivelycharged polysaccharide derived from oyster shells, is compared with slow releasefrom capsules strengthened with an outer membrane cross-linked with Ca2+.A third encapsulation exercise exploits the irreversible interfacial polymerizationof diamine and diacid chloride to form membranes and illustrates the detectionof diamine release from the capsule using an indicator.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::87c66d787d92e7615f71df419a758acb https://doi.org/10.1021/ed082p1017 Zobrazit plný text záznamu