Acylative kinetic resolution of 1,1′-binaphthyl-8,8′-diamines by organocatalysis

Autor:	Keisuke Yoshida, Valluru Krishna Reddy, Yasser Samir Abdel-Khalek Sokeirik, Keizo Kan, Takeo Kawabata, Yoshihiro Ueda, Masahiro Yamanaka, Atsushi Hirata
Rok vydání:	2022
Předmět:	Acylation Chemistry Organocatalysis Organic Chemistry Drug Discovery Enantioselective synthesis Organic chemistry Biochemistry Kinetic resolution Catalysis
Zdroj:	Tetrahedron. 103:132539
ISSN:	0040-4020
DOI:	10.1016/j.tet.2021.132539
Popis:	A method for kinetic resolution of 2,2′-disubstituted 1,1′-binaphthyl-8,8′-diamines has been developed by enantioselective acylation of the amino group with chiral pyrrolidinopyridine organocatalysts. Multiple hydrogen-bonding interactions as well as π-π interaction between the catalyst the diamines were proposed to be responsible for the accelerative enantioselective acylation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::877683297575a1642ae98a8b3348488a https://doi.org/10.1016/j.tet.2021.132539 Zobrazit plný text záznamu Full Text from ScienceDirect