Adrenal Lymphoma: Case Report and Review of Literature
| Autor: | Sushil Gupta, Archana Gupta, Amit Agarwal, Jaya Bhanu Kanwar |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Pathology business.industry Endocrinology Diabetes and Metabolism medicine.disease Lymphoma Primary Adrenal Insufficiency hemic and lymphatic diseases medicine Adrenal insufficiency Vomiting Radiology Nuclear Medicine and imaging Surgery Histopathology medicine.symptom Complication business Hyponatremia Generalized lymphadenopathy |
| Zdroj: | World Journal of Endocrine Surgery. 2:39-43 |
| ISSN: | 0975-7902 0975-5039 |
| DOI: | 10.5005/jp-journals-10002-1020 |
| Popis: | Adrenal lymphoma is a rare diagnosis in subject presenting with bilateral adrenal masses. Adrenal insufficiency is a common complication of this disease. Most cases of primary adrenal lymphoma (PAL) present with adrenal insufficiency and huge bilateral adrenal masses. These are very aggressive tumors with poor prognosis. We, hereby, report two subjects of adrenal lymphoma presenting with bilateral adrenal masses. First case is a 50 years old male presented with features of adrenal insufficiency like anorexia, weight loss, nausea, vomiting, and generalized hyperpigmentation. Routine investigations revealed hyponatremia, normal serum K; serum lactate dehydrogenase was moderately elevated. Primary adrenal insufficiency was confirmed by low basal and cosyntrophin stimulated cortisol. CT abdomen revealed huge bilateral heterogeneous enlargement of adrenal glands. Lymphoma was confirmed by histopathology and immunohistochemistry, diagnosis of PAL was made after further staging. He was treated with Rituximab-CHOP regimen. Second case, 50 years old lady presented with fever, anorexia, weight loss. She had generalized lymphadenopathy. On imaging found to have bilateral adrenal mass, and histopathology from lymph node, breast mass and adrenal mass was suggestive of non-Hodgkin's lymphoma. |
| Databáze: | OpenAIRE |
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