| Autor: |
Adi Pranoto, Purwo Sri Rejeki, Muhammad Miftahussurur, Hayuris Kinandita Setiawan, Ghana Firsta Yosika, Misbakhul Munir, Siti Maesaroh, Septyaningrum Putri Purwoto, Cakra Waritsu, Yoshio Yamaoka |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Journal of Basic and Clinical Physiology and Pharmacology. 34:235-242 |
| ISSN: |
2191-0286 |
| Popis: |
Objectives Regular treadmill exercise may result in changes in pro-inflammatory cytokines and oxidative stress. However, the way acute treadmill exercise mechanisms affect the changes in pro-inflammatory cytokines and oxidative stress in obese has not been comprehensively exposed. This study aimed to analyze the pro-inflammatory cytokines and oxidative stress between 30 min before treadmill exercise and 24 h after treadmill exercise in obese adolescents. Methods A total of 20 obese females aged 19–24 years were recruited from female students and given one session of treadmill exercise with an intensity of 60–70% HRmax. Thiobarbituric acid reactive substance (TBARS) was used to analyze serum levels of MDA, while enzyme-linked immunosorbent assay (ELISA) was used to analyze serum levels of TNF-α and IL-6. Moreover, the independent samples t-test with a significance level of 5% was employed to have the statistical analysis. Results The results on 24 h after treadmill exercise and delta (Δ) between CTRL and TREG showed a significant difference (p Conclusions This study found a decrease in pro-inflammatory cytokines and oxidative stress 24 h after treadmill exercise in obese adolescents. Therefore, treadmill exercise can be a promising strategy for preventing adolescents from obesity as well as preventing disease risks associated with oxidative stress and chronic inflammation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
