Retention in HIV Care Among HIV-Seropositive Pregnant and Postpartum Women in Uganda: Results of a Randomized Controlled Trial
Autor: | Allen L. Gifford, Harriet Chemusto, Davidson H. Hamer, Nafisa Halim, Rachael Bonawitz, Sivani Jonnalagadda, Lora Sabin, Mary Bachman DeSilva, Julia Gasuza, Lisa J. Messersmith, Philip Aroda, Elizabeth M. Simmons, Anna Larson Williams, Barbara Mukasa |
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Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
education.field_of_study Social Psychology business.industry Hiv seropositive Obstetrics Public health Population Public Health Environmental and Occupational Health law.invention Clinical trial Health psychology Infectious Diseases Randomized controlled trial law Pill Intervention (counseling) Medicine business education |
Zdroj: | AIDS and Behavior. 24:3164-3175 |
ISSN: | 1573-3254 1090-7165 |
Popis: | We tested an intervention that aimed to increase retention in antiretroviral therapy (ART) among HIV-positive pregnant and postpartum women, a population shown to be vulnerable to poor ART outcomes. 133 pregnant women initiating ART at 2 hospitals in Uganda used real time-enabled wireless pill monitors (WPM) for 1 month, and were then randomized to receive text message reminders (triggered by late dose-taking) and data-informed counseling through 3 months postpartum or standard care. We assessed “full retention” (proportion attending all monthly clinic visits and delivering at a study facility; “visit retention” (proportion of clinic visits attended); and “postpartum retention” (proportion retained at 3 months postpartum). Intention-to-treat and per protocol analyses found that retention was relatively low and similar between groups, with no significant differences. Retention declined significantly post-delivery. The intervention was unsuccessful in this population, which experiences suboptimal ART retention and is in urgent need of effective interventions. |
Databáze: | OpenAIRE |
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