Evaluation of the Du Pont Axial Separation system

Autor:	G A Adams, S L Perkins
Rok vydání:	1996
Předmět:	Separation system Analyte Chromatography Venipuncture Chemistry Biochemistry (medical) Clinical Biochemistry Blood plasma Analytical chemistry Becton dickinson Specimen Handling Sample preparation Vacutainer
Zdroj:	Clinical Chemistry. 42:1467-1473
ISSN:	1530-8561 0009-9147
Popis:	We evaluated the Du Pont Axial Separation Technology (AST) system, which permanently separates a blood specimen into serum or plasma and cells in 1 min. Blood was collected in axial processing containers by standard venipuncture techniques and processed in an Axial Separation Module. Paired patient samples (n = 48 serum pairs, n = 50 plasma pairs) revealed no clinically significant differences in results for common chemistry analytes from samples collected in Becton Dickinson Vacutainer Tubes and centrifuged conventionally vs those from samples collected and processed in the AST system, except for a bias in serum (but not plasma) lactate dehydrogenase activity. This bias was dependent on the extent of stretching of the clot during processing and could be minimized by clotting the blood sample horizontally (axially). We believe the rapid separation of blood by the AST system has the potential to substantially reduce preanalytical specimen handling time.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::83aa27f466bed18f43a9c7d869eb0080 https://doi.org/10.1093/clinchem/42.9.1467 Zobrazit plný text záznamu