The effects of ciprofloxacin on early life stages of common carp (Cyprinus carpio)
| Autor: | Jana Blahova, Lucie Chromcova, Misa Skoric, Stanislava Stepanova, Dana Zivna, Petr Marsalek, Eva Praskova, Miroslav Prokes, Lucie Plhalova, Zdenka Svobodova |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Health Toxicology and Mutagenesis 010501 environmental sciences 01 natural sciences Cyprinus Toxicology Andrology 03 medical and health sciences Common carp chemistry.chemical_compound medicine Environmental Chemistry 0105 earth and related environmental sciences chemistry.chemical_classification biology Hatching Glutathione peroxidase Glutathione biology.organism_classification Ciprofloxacin 030104 developmental biology chemistry Catalase Toxicity biology.protein medicine.drug |
| Zdroj: | Environmental Toxicology and Chemistry. 35:1733-1740 |
| ISSN: | 0730-7268 |
| Popis: | The authors performed a toxicity test with ciprofloxacin in fertilized eggs of common carp according to guideline 210 of the Organisation for Economic Co-operation and Development. The tested concentrations were 1 μg L(-1) , 100 μg L(-1) , 500 μg L(-1) , 1000 μg L(-1) , and 3000 μg L(-1) . Accelerated hatching was found in all groups exposed to ciprofloxacin, but significant growth reduction was found only in the group exposed to the highest concentration (3000 μg L(-1) ). Increased numbers of macroscopic morphological anomalies were observed on day 6 of the test (after hatching). The highest numbers of macroscopic morphological anomalies were observed in the groups of free embryos and larvae exposed to ciprofloxacin concentrations of 100 μg L(-1) , 500 μg L(-1) , 1000 μg L(-1) , and 3000 μg L(-1) (20-23% of tested samples). A gradual decrease in glutathione S-transferase activity was detected in all experimental groups exposed to ciprofloxacin, but significant differences (p |
| Databáze: | OpenAIRE |
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