Aryl Methyl Ketones: Versatile Synthons in the Synthesis of Heterocyclic Compounds

Autor: Mark Mitton-Fry, Jason West, Shabber Mohammed
Rok vydání: 2022
Předmět:
Zdroj: SynOpen. :110-131
ISSN: 2509-9396
DOI: 10.1055/a-1826-2852
Popis: The synthesis of aromatic heterocycles has attracted substantial attention due to the abundance of these heterocycles in drug molecules, natural products, and other compounds of biological interest. Accordingly, there is a demand for straightforward synthetic protocols toward such compounds using readily available starting materials. In the past decade, there have been substantial developments in heterocycle synthesis, especially in metal-catalyzed and iodine-assisted approaches. This graphical review focuses on notable reactions from the past decade using aryl and heteroaryl methyl ketones as starting materials, including representative reaction mechanisms.
Databáze: OpenAIRE