JMM Profile: Streptococcus pneumoniae: sugar-coated captain of the men of death

Autor:	Tina H. Dao, Jason W. Rosch
Rok vydání:	2021
Předmět:	Microbiology (medical) Pneumolysin business.industry Human pathogen General Medicine medicine.disease medicine.disease_cause Microbiology Pneumonia Antibiotic resistance Otitis Bacteremia Streptococcus pneumoniae medicine medicine.symptom business Pathogen
Zdroj:	Journal of Medical Microbiology. 70
ISSN:	1473-5644 0022-2615
DOI:	10.1099/jmm.0.001446
Popis:	Streptococcus pneumoniae is a highly adept human pathogen. A frequent asymptomatic member of the respiratory microbiota, the pneumococcus has a remarkable capacity to cause mucosal (pneumonia and otitis media) and invasive diseases (bacteremia, meningitis). In addition, the organism utilizes a vast battery of virulence factors for tissue and immune evasion. Though recognized as a significant cause of pneumonia for over a century, efforts to develop more effective vaccines remain ongoing. The pathogen’s inherent capacity to exchange genetic material is critical to the pneumococcus’ success. This feature historically facilitated essential discoveries in genetics and is vital for disseminating antibiotic resistance and vaccine evasion.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::81ef0e18572c64b9ea0e42f003ee5889 https://doi.org/10.1099/jmm.0.001446 Zobrazit plný text záznamu