A novel efficient route to hexahydrodibenzofuran derivatives
Autor: | F. Kigabo, Marie-Paule Jouannetaud, J.‐C. Jacquesy, Christian Berrier |
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Rok vydání: | 1991 |
Předmět: | |
Zdroj: | Tetrahedron. 47:6681-6688 |
ISSN: | 0040-4020 |
Popis: | Synthesis of 2 and 4-aryl cyclohexenones and of hexahydrodibenzofuran derivatives is described. In anhydrous hydrogen fluoride at 0°C, 4-hydroxy-4 methylcyclohex-2 en-1 one 2 reacted to yield ketone 7 (43%). Reaction of ketone 2 with parabromophenol 13b in HF gave ketone 6 (40%) at −20°C and ketone 6 (35%) and 7 (13%) at 0°C. Under similar conditions ketone 2 reacted with phenol 3a to yield 2 and 4 arylated ketones 4a (4%), 5 (a+b) (25%) and 9a (5%). |
Databáze: | OpenAIRE |
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