Treatment with Thiazides in Infants with Central Diabetes Insipidus
| Autor: | Madhia Shahid, Varshini Chakravarthy, Chirag R. Kapadia, Dorothee Newbern |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pediatrics
medicine.medical_specialty endocrine system diseases business.industry digestive oral and skin physiology urologic and male genital diseases medicine.disease Nephrogenic diabetes insipidus female genital diseases and pregnancy complications Hydrochlorothiazide Holoprosencephaly Diabetes insipidus Toxicity medicine business Desmopressin hormones hormone substitutes and hormone antagonists Thiazide Chlorothiazide medicine.drug |
| Zdroj: | Diabetes Insipidus in Children ISBN: 9783030832476 |
| DOI: | 10.1007/978-3-030-83248-3_14 |
| Popis: | Desmopressin, given orally, intranasally, or subcutaneously, is the conventional treatment for central diabetes insipidus. However, when used in infants, the risk of wide fluctuations in sodium levels and water toxicity increases. Thiazides, a class of diuretics, are the standard of care for treating nephrogenic diabetes insipidus. These have also shown efficacy in the management of central diabetes insipidus, particularly in infants. The following case illustrates the successful use of thiazides in treating an infant with central diabetes insipidus secondary to panhypopituitarism due to holoprosencephaly. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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