| Popis: |
Background and Objective: Chronic obstructive pulmonary disease (COPD) is predicted to be the third leading cause of death worldwide by 2020. Its diagnosis remains a challenge in developing countries such as DRC, with the use of Gold standard, spirometry, limited. Chest imaging plays an important role in orientation. The absence of local radiological data from COPD had therefore motivated this study. The aim of this study is to establish a relationship between gender, environment and COPD. Materials and Methods: Retrospective and analytical study of clinical and thoracic imaging data (radiography and CT scan), collected from the records of 120 COPD subjects followed in three Kinshasa medical trainings between January 2014 and June 2017. Fisher's test compared the results obtained. The combination of imaging data and clinical phenotype through Pearson chi-square testing, logistic regression and odds-ratio (OR). The service threshold was set at 0.05. Results: the study population (average age of 64.52±6.82 years) was predominantly male (78.3% n=94). Results: the study population (average age of 64.52±6.82 years) was predominantly male (78.3% n=94). The proportions of sputum were more common in men than in women, the difference being statistically significant. Indeed, the male sex confers a triple risk (OR=3.1; IC 95% 1.2-8; P=0.015). Women were more exposed to domestic and/or occupational pollution (65.4% n=17; than men were (26.6% n=25). Indeed, the male sex conferred a risk of exposure to domestic pollution and/or occupational pollution multiplied by 14 times (OR=14.3; IC 95%; 2-100; P=0.001) and allergy conferred a risk of exposure to domestic pollution by 17 times (OR=17.1; IC95%: 2.1-137, p=0.007). Conclusion: This study showed the male sex and allergy is conferred a high risk of the domestic pollution or occupation pollution. |
