Triglyceride to high-density lipoprotein cholesterol ratio and carotid intima-medial thickness in Chinese adolescents with newly diagnosed type 2 diabetes mellitus
| Autor: | Xin Li, Miao Yang, Yuwen Wu, Jiazhong Sun, Su-xin Sun, You-Ping Deng |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
endocrine system diseases Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism 030204 cardiovascular system & hematology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine High-density lipoprotein Insulin resistance Internal medicine Internal Medicine medicine cardiovascular diseases Triglyceride Cholesterol business.industry nutritional and metabolic diseases Type 2 Diabetes Mellitus Anthropometry medicine.disease Blood pressure Endocrinology chemistry Pediatrics Perinatology and Child Health cardiovascular system lipids (amino acids peptides and proteins) business Body mass index |
| Zdroj: | Pediatric Diabetes. 17:87-92 |
| ISSN: | 1399-543X |
| DOI: | 10.1111/pedi.12250 |
| Popis: | Objective To investigate the relationship between triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio and carotid intima-medial thickness (CIMT) in Chinese youth and adolescents with newly diagnosed type 2 diabetes mellitus (T2DM). Methods Ninety-eight subjects aged 10–24 yr with newly-diagnosed T2DM had general inflammation, anthropometric, laboratory and CIMT data collected, and were divided into three groups based on TG/HDL-C tertiles. Results There were no significant differences in gender, age, fasting plasma glucose (FPG), hemoglobin A1c (HbA1c), and carotid arterial diameter (CAD) among the groups based on TG/HDL-C tertiles. Across TG/HDL-C tertiles, there was a significant progressive increase in body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), homeostasis model assessment-estimated insulin resistance (HOMA-IR), TG, total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C) and CIMT (all P |
| Databáze: | OpenAIRE |
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