Effect of transplantation of human fetal tissue on central nervous system function in patients with the postcastration syndrome

Autor: E. M. Molnar, Z. M. Alikhanova, V. I. Kulakov, N. M. Tkachenko, Gennady T. Sukhikh
Rok vydání: 1994
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 117:383-387
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf02444191
Popis: Electrical activity of the brain was studied in 45 women after total oophorectomy in a state of calm alertness and in functional overload before and after transplantation of human fetal tissues. Pretransplantation studies showed α-rhythm disorganization, α-activity polyrhythmicity, a tendency toward high-frequency rhythms, and a disordered process of internal synchronization. Studies carried out after human fetal tissue transplantation showed adjustment of the cortex-stem relationships, a reduction of the α-rhythm index, and an increased β-activity index. Reactions to light stimuli and the function of the cerebral cortex improved in the majority of patients after transplantation, this being manifested in appropriate reactions to afferent stimulation. However, by the 6th month posttransplantation electrical activity of the brain was virtually the same as pretreatment.
Databáze: OpenAIRE