Une gammapathie monoclonale associée à un lymphome colique primitif à cellules du manteau
| Autor: | Ghorbel A, Asma Ouakaa, Dalila Gargouri, Afef Kilani, Jamel Kharrat, Asma Kochlef, Malika Romani, Belhadj N, G. Mohamed, Héla Elloumi |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Pathology
medicine.medical_specialty biology medicine.diagnostic_test business.industry Gastroenterology Immunoelectrophoresis medicine.disease Lymphoma medicine.anatomical_structure immune system diseases hemic and lymphatic diseases Immunopathology Monoclonal Immunology Internal Medicine biology.protein medicine Mantle cell lymphoma Rituximab Antibody business B cell medicine.drug |
| Zdroj: | La Revue de Médecine Interne. 30:279-281 |
| ISSN: | 0248-8663 |
| DOI: | 10.1016/j.revmed.2008.05.018 |
| Popis: | The association of a monoclonal gammopathy (MG) with a B cell non-Hodgkin's lymphoma (NHL) is a well-known phenomenon. It has been recognized in many subtypes of primary gastrointestinal lymphoma but its association with primary colonic mantle cell lymphoma has never been yet described. We report a 65-year-old man who presented with an exudative ascites and constipation. Serum electrophoresis showed a monoclonal peak in the gamma region of 45g/L and immunoelectrophoresis confirmed the presence of monoclonal gammopathy of IgM kappa type. Bone marrow aspirate was normal. Radiologic and endoscopic investigations evidenced a primary colonic mantle cell lymphoma. Although the association of an MG with an NHL and, in particular, to a primitive digestive location appears a rare phenomenon, endoscopic investigations in patients with MG appears legitimate in the presence of any digestive sign. |
| Databáze: | OpenAIRE |
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