The safety and efficacy of intrathecal morphine in pediatric spinal deformity surgery: a 25-year single-center experience
| Autor: | Christina K. Hardesty, Connie Poe-Kochert, George H. Thompson, Jochen P. Son-Hing, Kasia Petelenz Rubin, Jason Ina, Paul A. Tripi |
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| Rok vydání: | 2021 |
| Předmět: |
Pediatric intensive care unit
030222 orthopedics medicine.medical_specialty Nausea business.industry medicine.medical_treatment Kyphosis Scoliosis medicine.disease Single Center Surgery 03 medical and health sciences 0302 clinical medicine Spinal fusion Orthopedic surgery medicine Vomiting Orthopedics and Sports Medicine medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Spine Deformity. 9:1303-1313 |
| ISSN: | 2212-1358 2212-134X |
| DOI: | 10.1007/s43390-021-00320-8 |
| Popis: | Pre-incision intrathecal morphine (IM) is a popular adjunct in adolescent idiopathic spinal deformity surgery. This study represents our 25-year experience with IM in all diagnostic groups undergoing posterior spinal fusion (PSF) and segmental instrumentation (SI). Our prospective Pediatric Orthopaedic Spine Database (1992–2018) identified all patients undergoing PSF and SI. We included patients 21 years of age or less, had a PSF with SSI, and received the recommended IM dose of 9–19 mcg/kg (up to 1 mg) or no IM. We assessed demographics, pain scores, duration of surgery, time to first dose of narcotics, pediatric intensive care unit (PICU) admission, length of hospital stay, and IM complications (respiratory depression, pruritus, nausea/vomiting). There were 984 patients who met inclusion criteria: 760 patients received IM, 224 did not (non-IM). They were divided into 5 diagnostic groups: idiopathic, neuromuscular, syndromic, and congenital scoliosis and kyphosis. The mean first post-operative opioid following IM administration was at 16.1 h in the IM group compared to 8.7 h in the non-IM group (p = |
| Databáze: | OpenAIRE |
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