ChemInform Abstract: Stereocontrolled Approach to δ-Amino Acids by Asymmetric Hydrogenation of 5-Acetylaminopent-4-enoic Acid Derivatives

Autor:	E. V. Starodubtseva, Marina I. Struchkova, O. R. Malyshev, O. V. Turova, Zh. R. Sagirova, O. M. Antipova, M. G. Vinogradov
Rok vydání:	2011
Předmět:	chemistry.chemical_classification chemistry Asymmetric hydrogenation chemistry.chemical_element General Medicine Medicinal chemistry Rhodium Amino acid Catalysis
Zdroj:	ChemInform. 42
ISSN:	0931-7597
DOI:	10.1002/chin.201120036
Popis:	Asymmetric hydrogenation of the C=C bond in 5-acetylamino-5-phenylpent-4-enoic acid methyl ester or N,N-dimethylamide catalyzed by rhodium complexes with chiral bisphosphine ligands (1 mol.% of the catalyst, 20 atm. of H2, MeOH, 50 °C) gives the corresponding saturated derivatives with enantioselectivity up to 40% ??.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::795ae4ccd8685c2d5f54b376a93aa870 https://doi.org/10.1002/chin.201120036 Zobrazit plný text záznamu Plný text