Functional state of kidneys after injection of fetal liver cells to the rats with water and salt drinking regime under the conditions of acute sublimate nephropathy

Autor:	A. I. Hozhenko, О. О. Filipets, V. M. Sirman, N. D. Filipets
Rok vydání:	2016
Předmět:	chemistry.chemical_classification medicine.medical_specialty Fetus Chemistry Reabsorption media_common.quotation_subject Sodium Renal function chemistry.chemical_element Salt (chemistry) medicine.disease Urination Nephropathy Endocrinology Tap water Internal medicine medicine media_common
Zdroj:	Medical and Clinical Chemistry.
ISSN:	2414-9934 2410-681X
DOI:	10.11603/mcch.2410-681x.2016.v0.i1.6185
Popis:	The experiments on non linear white rats with acute sublimate nephropathy showed that in 7 days after intraperitoneal injection of fetal liver cells (FLC ) of rats plasma creatinine concentration decreased and proximal reabsorption of sodium ions increased independently of water or salt drinking regime. The increase of natremia in rats that used tap water excluded regulatory influence of FLC on the processes of maintenance of sodium balance under the conditions of experiment. Usage of 0.9 % NaCl solution leads to increase of glomerular filtration rate, activation of tubular transport of sodium ions with predominant elevation of reabsorption in the proximal part of nephron, reduction of sodium ions loss with urination. That points to substantial role of salt drinking regimen in additional beneficial effects of FLC on renal processes in rats with acute sublimate nephropathy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::79193bcd6764af7ee4b5dcc2683a3043 https://doi.org/10.11603/mcch.2410-681x.2016.v0.i1.6185 Zobrazit plný text záznamu