Double-Blind, Placebo-Controlled Food Challenges (DBPCFC) Demonstrating Acute IgE-Mediated Allergic Reactions to Good Start, Ultrafiltered Good Start, Alfaré, Nutramigen, and Alimentum in a Seven-Year-Old
| Autor: | Mark S. Amonette, Leisa Mattson, Donald M. Eldredge, Robert H. Schwartz, Linda B. Peers |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty business.industry Milk allergy Placebo medicine.disease Gastroenterology Hydrolysate Double blind Casein Nutramigen Internal medicine Pediatrics Perinatology and Child Health Immunology Immunology and Allergy Medicine Respiratory system business Soy protein |
| Zdroj: | Pediatric Asthma, Allergy & Immunology. 5:245-251 |
| ISSN: | 1557-7767 0883-1874 |
| DOI: | 10.1089/pai.1991.5.245 |
| Popis: | A 7-year-old girl with IgE-mediated cows' milk allergy (immediate reactor) underwent double-blind, placebo-controlled food challenge (DBPCFC) with three whey hydrolysate formulas (Good Start, Ultrafiltered Good Start, Alfare) and two casein hydrolysates (Nutramigen, Alimentum), using a soy protein formula (Isomil) as a control. She developed acute reactions to Good Start (3 ml; gastrointestinal, respiratory), Ultra Good Start (8 ml; respiratory, cutaneous), Alfare (158 ml; respiratory), Nutramigen (3 ml; respiratory, cutaneous), and Alimentum (4 ml; respiratory, cutaneous, gastrointestinal) and tolerated the Isomil control (318 ml) on three separate challenges under similar conditions. The generalized urticarial reactions to Nutramigen and Alimentum began 90 minutes after receiving less than 1 teaspoonful (3 ml and 4 ml, respectively) of formula. These observations indicate that all current commercially available cows' milk protein hydrolysate formulas can cause serious allergic reactions in the highly se... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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