Spatial response of jejunal pacing defined by a novel high-resolution multielectrode array

Autor: Nipuni D. Nagahawatte, Recep Avci, Niranchan Paskaranandavadivel, Timothy R. Angeli-Gordon, Leo K. Cheng
Rok vydání: 2023
Předmět:
Zdroj: American Journal of Physiology-Gastrointestinal and Liver Physiology. 324:G329-G340
ISSN: 1522-1547
0193-1857
DOI: 10.1152/ajpgi.00258.2022
Popis: A novel surface-contact electrode array customized for the small intestine anatomy enabled simultaneous pacing and high-resolution response mapping. The spatial response of small intestine bioelectrical activity to pacing was mapped for the first time in vivo. Antegrade and circumferential pacing achieved spatial entrainment over 70% of the time and their induced pattern was held for 4–6 cycles postpacing at high energy (4 mA, 100 ms, at ∼2.7 s which corresponds to 1.1 × intrinsic frequency).
Databáze: OpenAIRE