Long term efficacy of rituximab in follicular lymphoma (FL) and polymorphism in IgG Fc receptor FcγRIIIa/FcγRIIa genes

Autor:	Hervé Watier, Philippe Colombat, M. Orhesser, N. Varoqueaux, Guillaume Cartron, Philippe Solal-Celigny, Gilles Salles
Rok vydání:	2005
Předmět:	Antibody-dependent cell-mediated cytotoxicity Cancer Research biology business.industry Fc receptor Follicular lymphoma FCGR3A medicine.disease Oncology Immunology biology.protein Medicine Rituximab business Receptor Gene medicine.drug
Zdroj:	Journal of Clinical Oncology. 23:6598-6598
ISSN:	1527-7755 0732-183X
Popis:	6598 Background: FCGR3A coding for the FcγRIIIa receptor displays a functional dimorphism (FCGR3A-158V/F) and human IgG1 have a higher affinity for FCGR3A-158VV NK cells and increased ADCC compared...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::770742c54bbfcafedb1a07278d54a015 https://doi.org/10.1200/jco.2005.23.16_suppl.6598 Zobrazit plný text záznamu